Duloxetine is a new-generation antidepressant with minimal side effects and good tolerability. The drug is widely used in modern medicine for the treatment of anxiety and depressive disorders, as well as for reliving the neuropathic pain.

Duloxetine in Ireland is supplied by Wockhardt UK, Eli Lilly, Zentiva, Teva, KRKA, Rowex and Clonmel Healthcare. Local Irish retail pharmacies offer Duloxetine under the brand names Ariclaim, Xeristar, Cymbalta, Aritavi, Yentreve and Loxentia.

Duloxetine-containing products are available in form of capsules for oral use. You may use Duloxetine capsules of 20, 30, 40 or 60mg for the treatment of depression.

In retail pharmacies, Duloxetine is available with prescription. If a person wants to get Duloxetine without a prescription, he may order this antidepressant on an online pharmacy.

Timely started treatment gives quick results and allows minimizing the chance of depression symptoms aggravation, as well as the development of more severe mental disorders.

Before you start using Duloxetine, you should to read the instructions and indications for the use of this antidepressant.

Today, Duloxetine action mechanism and efficacy are well understood. The antidepressant has a double action and refers to serotonin and noradrenaline reuptake inhibitors.

Due to the wide spectrum of Duloxetine action, you may expect a relatively more rapid clinical response to therapy, than in therapy with other drugs.

In Ireland, Duloxetine antidepressant is approved for the treatment of:

  • Major depressive disorder;
  • Generalized anxiety disorder;
  • Chronic musculoskeletal pain;
  • Pain syndrome, associated with fibromyalgia and diabetic neuropathy;

Compared to other dual action inhibitors (like Venlafaxine), Duloxetine has a similar therapeutic efficacy. Yet, it is better tolerated in the titration period and may be prescribed to patients with hypertension.

Duloxetine advantages include its influence over the disturbing components of depressive disorders, as well as pain symptoms, associated with depression.

If you don’t have the opportunity to visit a specialist, and your back pain brings more discomfort with each passing day, you may buy Duloxetine online and start the pain treatment the next day.

For a quick Duloxetine purchase, Ireland’s people may use the services of local online pharmacies. Typically, these offer a number of Duloxetine-containing drugs that cost less, than in local retail pharmacy.

The online pharmacies, people may Duloxetine under various trade names, such as Duciltia, Strodros, Dutor, Baltine, Duloxecor, Tixol, Deotine, Coperin, Dytrex, and Depreta.

However, we recommend you to carefully read the instructions for use and the dosing regimen of Duloxetine before you start taking this antidepressant, because it affects the efficiency and safety of the treatment.

Duloxetine affects both serotonergic and noradrenergic systems, and is not inferior to tricyclic antidepressants (e.g., Trimipramine) by the effectiveness of the anxiety-depressive disorders treatment.

Dosage and duration of Duloxetine use should be selected individually, depending on the tolerability and patient’s clinical response to treatment.

The recommended initial dose of Duloxetine for the major depressive disorder treatment in adults is 40 to 60 mg, taken once a day, regardless of the food intake. The daily dose for the elderly and patients with impaired renal function should not exceed 30 mg of Duloxetine.

Some patients may require the dose increase from 60 mg (once a day) to a maximum dose of 120 mg per day (divided in two intakes) to achieve a good result.

If you are in search of a safe and effective antidepressant for an elderly person, choose Duloxetine. Studies have shown that the drug provides rapid antidepressant effects and is well tolerated by elderly patients.

If the cost of the drug in the Irish retail pharmacies is high for you, order cheap Duloxetine on the online pharmacies. Before you buy Duloxetine online, you should figure, what are the terms of delivery and the total cost of the order. It should be understood that the price of the drug will depend on the quantity of Duloxetine capsules ordered. The larger the dose of the antidepressant you order, the lower the cost of each dose.

Duloxetine efficacy for the treatment of painful diabetic peripheral neuropathy has been proven in three double-blind, placebo-controlled trials.

The results showed that Duloxetine at a dosage of 60 mg per day in a short 12-weeks course, is an effective treatment method for peripheral neuropathy and fibromyalgia.

It should be borne in mind that Duloxetine is a second-line drug for the treatment of painful diabetic neuropathy form in adults.

This antidepressant may be used to treat neuropathic pain, when treatment with anticonvulsants did not bring a resistant positive effect.

When Duloxetine was compared to the standard neuropathic pain therapy, the drug showed sufficient safety and tolerability. Duloxetine safety and tolerability study showed that the incidence of adverse effects depends on the dose used.

The most common adverse events of high Duloxetine dose of 60 mg is drowsiness, nausea, weakness, dizziness and constipation. When using of the higher Duloxetine dose of 120mg, these reactions were observed more frequently.

However, the undesirable effects in majority of patients are mild in nature and are self-reduced by 1-2 weeks of Duloxetine use.

The antidepressant has the ability to increase the pain threshold in the neuropathic etiology pain syndrome. People, who want to start a fast treatment of neuropathic pain, may buy Duloxetine without a prescription on an online pharmacy.

Today, Duloxetine is one of the mostly prescribed antidepressants in Ireland. The research results indicate a good anxiolytic and timoanaleptic activity of the drug.