Mirtazapine is a tetracyclic antidepressant, which was first synthesized in 1994 by the pharmaceutical company Organon. This antidepressant has strong sedative and anxiolytic properties.
Mirtazapine is supplied to the Irish market in the form of film-coated and orodispersible tablets in three dosages: 15, 30 or 45 mg. The Irish may also buy Mirtazapine as 15mg/ml oral solution, packaged in dark glass vials of 66ml.
Choosing one or another form of the antidepressant depends on the patient’s preferences, ease of use and the drug cost. It is believed that the price of film-coated Mirtazapine tablets is slightly lower than the cost of orodispersible tablets.
This antidepressant refers to psychotropic medicines and is sold in local retail chains with a prescription. If a person has no opportunity to get to a specialist and get a prescription for this antidepressant, he may order Mirtazapine without prescription on an online pharmacy.
Before you buy Mirtazapine, patient is recommended to find out the exact indications for the use and benefits of this antidepressant, compared to other psychotropic drugs.
Mirtazapine is approved in Ireland for the treatment of major depressive disorder in adolescents aged 18 and older, adults and the elderly. Anxiolytic and hypnotic properties manifest in clinical conditions, due to which the drug may be used in anxiety depressions.
The antidepressant possesses a unique profile of pharmacological activity and blocks adrenergic receptors, thus promoting the norepinephrine and serotonin release.
The action mechanism of Mirtazapine is aimed at improving the nervous pulse transmission in the noradrenergic and serotonergic neurotransmitter systems.
The antidepressant has a great affinity for H1- histamine receptors, and at the same time a low affinity for dopamine receptors, which plays an important role in the treatment of clinical depression.
Studies have shown a comparable efficacy of Mirtazapine with such antidepressants, as Venlafaxine, Fluoxetine, and Paroxetine. Yet, at the same time, a slight Mirtazapine advantage was recorded at different treatment stages, which is marked through a rapid onset of the antidepressant effect.
An important component of Mirtazapine antidepressant action is its ability to quickly reduce sleep disturbances in patients with depression.
Therefore, if the patient suffers from insomnia or frequent night awakenings, associated with depression, you may buy Mirtazapine online for sleep normalization.
Clinical studies have shown that this antidepressant significantly reduces the period of sleep onset, reduces the number of nighttime awakenings, and increases the duration and quality of sleep.
Regardless of whether you bought this antidepressant in the retail drug store or ordered online, all patients are advised to familiarize themselves with the drug dosing schedule before they start using Mirtazapine.
Mirtazapine should be taken once a day, in the evening before bedtime. The average therapeutic doses range from 15 to 45 mg per day. The recommended starting dose of Mirtazapine is 15 mg, which may gradually increased up to 45 mg per day, if necessary.
The duration of the depression treatment is determined individually, depending on the disease severity. However, as studies show, treatment with Mirtazapine should continue for at least 6 months to relieve depressive symptoms.
The cost of depression treatment with this antidepressant is high. This is why many patients are interested in where to buy cheap Mirtazapine in Ireland.
If you are in search of cheap tetracyclic antidepressant, you may buy Mirtazapine on an online pharmacy. The online cost of online depends on the amount of pills or oral solution packages you order.
The more packages Mirtazapine you order at once, the higher the discount, and, consequently, the lower cost of tablets. If you decide to order Mirtazapine oral solution, you should know that the drug is suitable for use for 6 weeks after you open the vial.
Oral solution and oral Mirtazapine tablets are bioequivalent and have the same therapeutic effect. Reduction of depression symptoms usually fixes already by the end of the second – beginning of the third week of the antidepressant administration.
Mirtazapine is well tolerated in therapeutic doses, and does not affect the cardiovascular system, so this antidepressant may be used in elderly patients.
Yet, like other antidepressants, Mirtazapine is not devoid of side effects. Approximately 10-30% of patients may experience excessive sleepiness, weight gain, and headaches at the beginning of therapy.
In comparison with Duloxetine and Paroxetine, Mirtazapine is less likely to cause sexual dysfunction, while as blood pressure and heart activity indicators do not change.
The Irish may buy Mirtazapine in local pharmacies under the trade name Zispin, Mirap, and Zismirt. Mirtazapine-containing medicines are presented on the online pharmacies much broader and are available under the brand names Remeron, Norset, Milivin, Axit, Mirtazon, Avanza, Mirta, and Remergil.
Today, Mirtazapine is the first choice antidepressant in the treatment of patients with major depressive disorder. The lack of significant side effects and clinically significant drug interactions, allows recommending Mirtazapine as a basic component of the treatment scheme for the neurological patients.